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1

Modification of buccal drug delivery following pretreatment with skin penetration enhancers

Joseph A. Nicolazzo, Barry L. Reed, Barrie C. Finnin

Journal:

Journal of Pharmaceutical Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 172 KB

english, 2004

2

A Tribute to Ronald T. Borchardt—Teacher, Mentor, Scientist, Colleague, Leader, Friend, and Family Man

Schowen, Katharine Barbara, Schowen, Richard L., Borchardt, Susan E., Borchardt, Paul M., Artursson, Per, Audus, Kenneth L., Augustijns, Patrick, Nicolazzo, Joseph A., Raub, Thomas J., Schöneich, Chri

Journal:

Journal of Pharmaceutical Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 238 KB

english, 2016

3

Assessing the Impact of Lithium Chloride on the Expression of P-Glycoprotein at the Blood-Brain Barrier

Newman, Stephanie A., Pan, Yijun, Short, Jennifer L., Nicolazzo, Joseph A.

Journal:

Journal of Pharmaceutical Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 910 KB

english, 2017

4

Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake

Ojeda, Paola G., Henriques, Sónia Troeira, Pan, Yijun, Nicolazzo, Joseph A., Craik, David J., Wang, Conan K.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2017

5

Dietary Docosahexaenoic Acid Supplementation Enhances Expression of Fatty Acid-Binding Protein 5 at the Blood-Brain Barrier and Brain Docosahexaenoic Acid Levels

Pan, Yijun, Morris, Elonie R, Scanlon, Martin J, Marriott, Philip J, Porter, Christopher JH, Nicolazzo, Joseph A

Journal:

Journal of Neurochemistry

Année:

2018

Langue:

english

Fichier:

PDF, 414 KB

english, 2018

6

The effect of various in vitro conditions on the permeability characteristics of the buccal mucosa

Joseph A. Nicolazzo, Barry L. Reed, Barrie C. Finnin

Journal:

Journal of Pharmaceutical Sciences

Année:

2003

Langue:

english

Fichier:

PDF, 267 KB

english, 2003

7

Assessment of the effects of sodium dodecyl sulfate on the buccal permeability of caffeine and estradiol

Joseph A. Nicolazzo, Barry L. Reed, Barrie C. Finnin

Journal:

Journal of Pharmaceutical Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 189 KB

english, 2004

8

Enhanced buccal mucosal retention and reduced buccal permeability of estradiol in the presence of padimate O and Azone®: A mechanistic study

Joseph A. Nicolazzo, Barry L. Reed, Barrie C. Finnin

Journal:

Journal of Pharmaceutical Sciences

Année:

2005

Langue:

english

Fichier:

PDF, 153 KB

english, 2005

9

A novel flow through diffusion cell for assessing drug transport across the buccal mucosa in vitro

Maria L.A.D. Lestari, Joseph A. Nicolazzo, Barrie C. Finnin

Journal:

Journal of Pharmaceutical Sciences

Année:

2009

Langue:

english

Fichier:

PDF, 310 KB

english, 2009

10

The buccal mucosa as an alternative route for the systemic delivery of risperidone

Lars B. Heemstra, Barrie C. Finnin, Joseph A. Nicolazzo

Journal:

Journal of Pharmaceutical Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 256 KB

english, 2010

11

Effective use of reducing agents and nanoparticle encapsulation in stabilizing catechins in alkaline solution

Admire Dube, Ken Ng, Joseph A. Nicolazzo, Ian Larson

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 558 KB

english, 2010

12

Assessment of plasma concentrations of (−)-epigallocatechin gallate in mice following administration of a dose reflecting consumption of a standard green tea beverage

Admire Dube, Joseph A. Nicolazzo, Ian Larson

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 385 KB

english, 2011

13

Brain uptake of diazepam and phenytoin in a genetic animal model of absence epilepsy

Joseph A Nicolazzo, Jessica A Steuten, Susan A Charman, Nerida Taylor, Philip J Davies, Steven Petrou

Journal:

Clinical and Experimental Pharmacology and Physiology

Année:

2010

Langue:

english

Fichier:

PDF, 175 KB

english, 2010

14

Methods to assess drug permeability across the blood-brain barrier

Joseph A. Nicolazzo, Susan A. Charman, William N. Charman

Journal:

Journal of Pharmacy and Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 511 KB

english, 2006

15

Pharmacokinetics and brain uptake of AM-36, a novel neuroprotective agent, following intravenous administration to rats

Joseph A. Nicolazzo, Tien T. Nguyen, Kasiram Katneni, Jessica A. Steuten, Gregg Smith, Bevyn Jarrott, Jennifer K. Callaway, Susan A. Charman

Journal:

Journal of Pharmacy and Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 225 KB

english, 2008

16

Chitosan nanoparticles enhance the intestinal absorption of the green tea catechins (+)-catechin and (−)-epigallocatechin gallate

Admire Dube, Joseph A. Nicolazzo, Ian Larson

Journal:

European Journal of Pharmaceutical Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 249 KB

english, 2010

17

Chitosan nanoparticles enhance the plasma exposure of (−)-epigallocatechin gallate in mice through an enhancement in intestinal stability

Admire Dube, Joseph A. Nicolazzo, Ian Larson

Journal:

European Journal of Pharmaceutical Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 377 KB

english, 2011

18

Synergistic enhancement of testosterone transdermal delivery

Joseph A. Nicolazzo, Timothy M. Morgan, Barry L. Reed, Barrie C. Finnin

Journal:

Journal of Controlled Release

Année:

2005

Langue:

english

Fichier:

PDF, 151 KB

english, 2005

19

Enhancing the buccal mucosal uptake and retention of triamcinolone acetonide

Joseph A. Nicolazzo, Barry L. Reed, Barrie C. Finnin

Journal:

Journal of Controlled Release

Année:

2005

Langue:

english

Fichier:

PDF, 143 KB

english, 2005

20

Buccal penetration enhancers—How do they really work?

Joseph A. Nicolazzo, Barry L. Reed, Barrie C. Finnin

Journal:

Journal of Controlled Release

Année:

2005

Langue:

english

Fichier:

PDF, 663 KB

english, 2005

21

The Involvement of a Na + - and Cl – -Dependent Transporter in the Brain Uptake of Amantadine and Rimantadine

Kooijmans, Sander A. A., Senyschyn, Danielle, Mezhiselvam, Muguntha M., Morizzi, Julia, Charman, Susan A., Weksler, Babette, Romero, Ignacio-Andres, Couraud, Pierre-Olivier, Nicolazzo, Joseph A.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 353 KB

english, 2012

22

Computational Prediction of CNS Drug Exposure Based on a NovelIn VivoDataset

Christel A. S. Bergström, Susan A. Charman, Joseph A. Nicolazzo

Journal:

Pharmaceutical Research

Année:

2012

Langue:

english

Fichier:

PDF, 540 KB

english, 2012

23

Expression of Tryptophan 2,3-Dioxygenase and Production of Kynurenine Pathway Metabolites in Triple Transgenic Mice and Human Alzheimer's Disease Brain

Wu, Wei, Nicolazzo, Joseph A., Wen, Li, Chung, Roger, Stankovic, Roger, Bao, Shisan S., Lim, Chai K., Brew, Bruce J., Cullen, Karen M., Guillemin, Gilles J., Adlard, Paul A.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 3.70 MB

english, 2013

24

Altered Brain Uptake of Therapeutics in a Triple Transgenic Mouse Model of Alzheimer’s Disease

Dharmini C. Mehta, Jennifer L. Short, Joseph A. Nicolazzo

Journal:

Pharmaceutical Research

Année:

2013

Langue:

english

Fichier:

PDF, 466 KB

english, 2013

25

Memantine Transport across the Mouse Blood–Brain Barrier Is Mediated by a Cationic Influx H + Antiporter

Mehta, Dharmini C., Short, Jennifer L., Nicolazzo, Joseph A.

Journal:

Molecular Pharmaceutics

Année:

2013

Langue:

english

Fichier:

PDF, 368 KB

english, 2013

26

The Lymphatic System Plays a Major Role in the Intravenous and Subcutaneous Pharmacokinetics of Trastuzumab in Rats

Dahlberg, Annette M., Kaminskas, Lisa M., Smith, Alanna, Nicolazzo, Joseph A., Porter, Christopher J. H., Bulitta, Jürgen B., McIntosh, Michelle P.

Journal:

Molecular Pharmaceutics

Année:

2014

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2014

27

Synthesis, Structure–Activity Relationships and Brain Uptake of a Novel Series of Benzopyran Inhibitors of Insulin-Regulated Aminopeptidase

Mountford, Simon J., Albiston, Anthony L., Charman, William N., Ng, Leelee, Holien, Jessica K., Parker, Michael W., Nicolazzo, Joseph A., Thompson, Philip E., Chai, Siew Yeen

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 2.60 MB

english, 2014

28

4880732 Process for the rapid determination of sperm cell count and/or living sperm count

Mehta, Dharmini C., Short, Jennifer L., Nicolazzo, Joseph A.

Journal:

Biotechnology Advances

Année:

1990

Langue:

english

Fichier:

PDF, 69 KB

english, 1990

29

Reduced CNS exposure of memantine in a triple transgenic mouse model of Alzheimer's disease assessed using a novel LC–MS technique

Mehta, Dharmini C., Short, Jennifer L., Nicolazzo, Joseph A.

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2013

Langue:

english

Fichier:

PDF, 361 KB

english, 2013

30

Biodistribution of polymer hydrogel capsules for the delivery of therapeutics

Hinton, Tracey M., Monaghan, Paul, Green, Diane, Kooijmans, Sander A.A., Shi, Shuning, Breheney, Kerry, Tizard, Mark, Nicolazzo, Joseph A., Zelikin, Alexander N., Wark, Kim

Journal:

Acta Biomaterialia

Année:

2012

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2012

31

Overexpression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase in triple-transgenic (3xTg) Alzheimer's disease mouse brain

Wu, Wei, Nicolazzo, Joseph, Chung, Roger, Cullen, Karen, Ball, Helen, Guillemin, Gilles

Journal:

Alzheimer's & Dementia

Année:

2011

Langue:

english

Fichier:

PDF, 49 KB

english, 2011

32

Decreased blood–brain barrier expression of P-glycoprotein in Alzheimer’s disease: impact on pathogenesis and brain access of therapeutic agents

Nicolazzo, Joseph A, Banks, William A

Journal:

Therapeutic Delivery

Année:

2011

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2011

33

Azone® Decreases the Buccal Mucosal Permeation of Diazepam in a Concentration-Dependent Manner via a Reservoir Effect

Meng-Lund, Emil, Jacobsen, Jette, Jin, Liang, Janfelt, Christian, Holm, René, Müllertz, Anette, Nicolazzo, Joseph A.

Journal:

Journal of Pharmaceutical Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 939 KB

english, 2014

34

The Effect of Formulation Excipients on the Penetration and Lateral Diffusion of Ibuprofen on and within the Stratum Corneum Following Topical Application to Humans

Gee, Carol M., Watkinson, Adam C., Nicolazzo, Joseph A., Finnin, Barrie C.

Journal:

Journal of Pharmaceutical Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 3.32 MB

english, 2014

35

Exploiting the Buccal Mucosa as an Alternative Route for the Delivery of Donepezil Hydrochloride

Caon, Thiago, Pan, Yijun, Simões, Cláudia M. O., Nicolazzo, Joseph A.

Journal:

Journal of Pharmaceutical Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 448 KB

english, 2014

36

Buccal mucosal delivery of a potent peptide leads to therapeutically-relevant plasma concentrations for the treatment of autoimmune diseases

Jin, Liang, Boyd, Ben J., White, Paul J., Pennington, Michael W., Norton, Raymond S., Nicolazzo, Joseph A.

Journal:

Journal of Controlled Release

Année:

2015

Langue:

english

Fichier:

PDF, 712 KB

english, 2015

37

Enhancing the Buccal Mucosal Delivery of Peptide and Protein Therapeutics

Caon, Thiago, Jin, Liang, Simões, Cláudia M. O., Norton, Raymond S., Nicolazzo, Joseph A.

Journal:

Pharmaceutical Research

Année:

2015

Langue:

english

Fichier:

PDF, 969 KB

english, 2015

38

Drug Access to the Central Nervous System in Alzheimer’s Disease: Preclinical and Clinical Insights

Mehta, Dharmini C., Short, Jennifer L., Hilmer, Sarah N., Nicolazzo, Joseph A.

Journal:

Pharmaceutical Research

Année:

2015

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2015

39

Fatty Acid Binding Proteins Expressed at the Human Blood–Brain Barrier Bind Drugs in an Isoform-Specific Manner

Lee, Gordon S., Kappler, Katharina, Porter, Christopher J. H., Scanlon, Martin J., Nicolazzo, Joseph A.

Journal:

Pharmaceutical Research

Année:

2015

Langue:

english

Fichier:

PDF, 2.53 MB

english, 2015

40

Fatty acid-binding protein 5 facilitates the blood-brain barrier transport of docosahexaenoic acid

Pan, Yijun, Scanlon, Martin J, Owada, Yuji, Yamamoto, Yui, Porter, Christopher J.H., Nicolazzo, Joseph A.

Journal:

Molecular Pharmaceutics

Année:

2015

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2015

41

Quantitation of Polymyxin–Lipopolysaccharide Interactions Using an Image-Based Fluorescent Probe

McInerney, Mitchell P., Roberts, Kade D., Thompson, Philip E., Li, Jian, Nation, Roger L., Velkov, Tony, Nicolazzo, Joseph A.

Journal:

Journal of Pharmaceutical Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 609 KB

english, 2016

42

Pulmonary Delivery of the Kv1.3-Blocking Peptide HsTX1[R14A] for the Treatment of Autoimmune Diseases

Jin, Liang, Zhou, Qi (Tony), Chan, Hak-Kim, Larson, Ian C., Pennington, Michael W., Morales, Rodrigo A.V., Boyd, Ben J., Norton, Raymond S., Nicolazzo, Joseph A.

Journal:

Journal of Pharmaceutical Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 587 KB

english, 2016

43

Enabling Noninvasive Systemic Delivery of the Kv1.3-Blocking Peptide HsTX1[R14A] via the Buccal Mucosa

Jin, Liang, Boyd, Ben J., Larson, Ian C., Pennington, Michael W., Norton, Raymond S., Nicolazzo, Joseph A.

Journal:

Journal of Pharmaceutical Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 562 KB

english, 2016

44

Drug Transport Across the Blood-Brain Barrier and the Impact of Breast Cancer Resistance Protein (ABCG2)

Nicolazzo, Joseph, Katneni, Kasiram

Journal:

Current Topics in Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 430 KB

english, 2009

45

Transport of drugs across the blood–brain barrier in Alzheimer’s disease

Nicolazzo, Joseph A, Mehta, Dharmini C

Journal:

Therapeutic Delivery

Année:

2010

Langue:

english

Fichier:

PDF, 2.12 MB

english, 2010

46

Development and Validation of an In-Cell Western for Quantifying P-Glycoprotein Expression in Human Brain Microvascular Endothelial (hCMEC/D3) Cells

McInerney, Mitchell P., Pan, Yijun, Short, Jennifer L., Nicolazzo, Joseph A.

Journal:

Journal of Pharmaceutical Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2017

47

Neurovascular Alterations in Alzheimer’s Disease: Transporter Expression Profiles and CNS Drug Access

Mitchell P. McInerney,Jennifer L. Short,Joseph A. Nicolazzo

Journal:

The AAPS Journal

Année:

2017

Langue:

english

Fichier:

PDF, 1.80 MB

english, 2017

48

Reduced Blood-Brain Barrier Expression of Fatty-Acid Binding Protein 5 is associated with Increased Vulnerability of APP/PS1 mice to Cognitive Deficits from Low Omega-3 Fatty Acid Diets

Pan, Yijun, Choy, Kwok H C, Marriott, Philip J, Chai, Siew Y, Scanlon, Martin J, Porter, Christopher J. H, Short, Jennifer L, Nicolazzo, Joseph A

Journal:

Journal of Neurochemistry

Année:

2017

Langue:

english

Fichier:

PDF, 444 KB

english, 2017

49

Fatty Acid–Binding Protein 5 Mediates the Uptake of Fatty Acids, but not Drugs, Into Human Brain Endothelial Cells

Lee, Gordon S., Pan, Yijun, Scanlon, Martin J., Porter, Christopher J.H., Nicolazzo, Joseph A.

Journal:

Journal of Pharmaceutical Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 823 KB

english, 2017

50

Effect of Permeation Enhancers on the Buccal Permeability of Nicotine: Ex vivo Transport Studies Complemented by MALDI MS Imaging

Marxen, Eva, Jin, Liang, Jacobsen, Jette, Janfelt, Christian, Hyrup, Birgitte, Nicolazzo, Joseph A.

Journal:

Pharmaceutical Research

Année:

2018

Langue:

english

Fichier:

PDF, 4.63 MB

english, 2018